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• Genetic-Morphological Synergy Governs Cell Fate Specification in Development

  作者: Guoye Guan，Yixuan Chen，Hongli Wang

  摘要:

  Cell morphology reflects cellular states, particularly cell fates with specific spatiotemporal features, like the spreading of epidermal cells in skin. However, how cell morphology relates to cell fate and genetic programs remains unclear. In this study, we leveraged the up-to-date lineage-resolved 3D cell morphology dataset of worm Caenorhabditis elegans embryogenesis. Twelve quantitative...

  关键词: cell morphology; gene expression; cell fate differentiation; coupling and decoupling; metazoan development; germ layer; tissue and organ; body axis; Caenorhabditis elegans embryogenesis

  发布于: 首次发布 2025-12-16

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